SmallinterferingRNA相关论文
目的:研究以小干扰RNA(siRNA)阻断Notch1、Notch2、Notch3和Notch4各亚型对支气管哮喘(哮喘)模型小鼠肺T细胞分化的影响,比较Notch......
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System-wide analysis reveal proteins involved in cis-9,trans-11 conjugated linoleic acid synthesis i
Cis-9,trans-11 conjugated linoleic acid (CLA) exists predominantly in ruminant products because of the unique physiologi......
The specific and robust effect of RNA interference on gene expression renders small interfering RNA(siRNA)a valuable the......
Cell-penetrating peptides (CPPs),which can efficiently facilitate the cellular uptake of various payloads without causin......
Thymosin β 4 activates integrin-linked kinase and decreases endothelial progenitor cells apoptosis u
Thymosin β 4 (T β 4) has been suggested to regulate multiple cell signal pathways and a variety of cellular functions ......
Designs on the redox-sensitive targeting drug and gene co-delivery based on “intracellular triggered
Cationic polymers such as branched poly(ethylenimine) (PEI) have been well-studied due to their superior gene transfecti......
BTF3 (Basic Transcription Factor 3),a transcription factor and modulator of apoptosis,is differentially expressed in car......
Inhibiting glucose transporter-1 and the PI3K/Akt pathway with apigenin, siRNA, LY294002 or wortmann
Background We first hypothesized that targeting glucose transporter-1 (GLUT-1) and the phosphatidylinositol 3-kinase/pro......
α-Catenin Inactivation Disrupts Expression of Intercalated Disc Protein and Alters Physiological Fun
α-Catenin is a key cell adhesion protein that is thought to indispensably link the cadherin-based adhesion complex to t......
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Expression of HAbl8G in non-small lung cancer and its effects on biology behaviors of lung cell line
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Cancer treatment still faces a lot of obstacles such as tumor heterogeneity,drug resistance and systemic toxicities.Beyo......
Effect of RNA Interference Targeting STAT3 Gene Combined with Ultrasonic Irradiation and SonoVue Mic
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RNA干扰( RNAi)技术是利用双链 RNA,高效、特异性降解细胞内同源信使 RNA,从而阻断特定基因表达,使细胞出现靶基因缺失的表型。与反义寡......
目的探讨缺氧环境下活化的血管内皮细胞是否可诱导SNAI1表达上调,进而通过SNAI1-基质金属蛋白酶(MMP)2和MMP9途径参与CNV生成。方法......
Effects of Small Interfering RNA Targeting Sphingosine Kinase-1 Gene on the Animal Model of Alzheime
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Small Interfering RNA Targeting TNF-α Gene Significantly Attenuates Renal Ischemia-Reperfusion、Injur
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Effects of RNA Interference Combined with Ultrasonic Irradiation and SonoVue Microbubbles on Express
The most effective sequence of small interfering RNA (siRNA) silencing STAT3 of psoriatic keratinocytes (KCs) was screen......
目的:研究S100B在多柔比星诱导心肌细胞损伤中的表达变化及作用.方法:将体外培养的心肌细胞随机分为对照组,多柔比星损伤组(DOX组)......
As a new treatment technique,photothermal therapy(PTT)has aroused worldwide attention in cancer treatment,mainly due to ......
KNOCKDOWN OF SURVIVIN EXPRESSION BY SMALL INTERFERING RNA SUPPRESSES PROLIFERATION OF TWO HUMAN CANC
Objective To construct an expression vector of small interfering RNA (siRNA) against survivin and observe its effects on......
目的 应用小干扰RNA(siRNA)干扰胰腺癌PANC-1细胞的c-Src表达,为后续试验做准备.方法 将c-Src siRNA,经LipofectamineTM2000脂质体......
目的:研究miR-155特异性siRNA增强阿糖胞苷(Ara-C)诱导的Burkitt淋巴瘤Raji细胞凋亡及其机制。方法:Ara-C与miR-155 siRNA单独或者联合......